Loneliness has become a significant public health issue due to its impact on longevity, mental and physical health, and general well-being.
The latest study, published in Aging and Mental Health, adds further weight to the strong links between feeling lonely and brain function in older adults.
The research was conducted by scientists from Spain, Sweden and Colombia.
They say the findings also reinforce the theory that isolation is not necessarily a risk factor for dementia.
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The team suggests that regular loneliness screening could be included in checks to test mental abilities in older adults.
Study lead author Dr. Luis Carlos Venegas-Sanabria said: "The finding that loneliness significantly impacted memory, but not the speed of decline in memory over time was a surprising outcome.
"It suggests that loneliness may play a more prominent role in the initial state of memory than in its progressive decline."
He says loneliness and social isolation are among the most relevant risk factors for dementia.
But data on the link between loneliness and cognitive function are inconsistent.
Some studies suggest loneliness accelerates cognitive decline over time while others have found no significant link.
The aim of the new study was to assess the effect of loneliness on how memory changes over a seven-year period.
The analysis used data covering 2012 to 2019 from SHARE, a survey launched in 2002 that examines the health and aging of Europeans ages 50 and over.
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Participants were from countries including Germany, Slovenia, Spain and Sweden. The 12 countries were grouped into four geographic regions: Central, South, North and Eastern.
Anyone with a history of dementia, including Alzheimer's disease, was excluded along with those whose activities related to daily living were "impaired" — classified as people who have any disability in activities such as walking, eating or taking a shower.
Memory was assessed as the ability to recall information immediately and after a time delay.
Tests included participants having to remember as many words as possible in a minute from a 10-word list that was read aloud.
Researchers asked participants three questions to measure their loneliness and to categorize them into low, average or high.
The questions included "How much of the time do you feel you lack companionship?" and "How much of the time do you feel left out?"
Researchers also assessed physical activity, engagement in social activities, depression scores, diabetes and other factors that could potentially influence the research.
Results showed Southern European countries reported the highest levels of loneliness (12%) followed by the Eastern region (9%), Central (6%) and Northern (9%) regions.
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Overall, the majority of participants (92%) reported either average or low levels of loneliness at the start of the research.
The group with high levels (8%) was older, mostly female and self-reported worse health issues. They also had a higher prevalence of depression, high blood pressure and diabetes.
Those in the "high" category had lower immediate and delayed recall scores at the beginning of the study compared to those with lower loneliness levels.
But they experienced a rate of decline in memory similar to that of participants in the low and average loneliness categories.
The steep "slope" was observed between the assessments at year three and year seven, according to the findings.
Dr. Venegas-Sanabria, of Universidad del Rosario, Bogota, Colombia, added: "The study underscores the importance of addressing loneliness as a significant factor in the context of cognitive performance in older adults."
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